BiochemistrybioRxivPreprint
27-hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor
S. Ayadi, S. Friedrichs, R. Soules…·P. de Medina
The paper shows that CYP27A1 converts OCDO into 27H-OCDO, which inhibits breast cancer cell proliferation, switching its activity from pro-tumor to anti-tumor.
DOI 10.1101/2023.10.10.560948