CRYPTOCHROME suppresses the circadian proteome and promotes protein homeostasis
D. C. S. Wong, E. Seinkmane, A. Stangherlin, A. Zeng, N. M. Rzechorzek, A. D. Beale, J. Day, M. Reed, S. Y. Peak-Chew, C. T. Styles, R. S. Edgar, M. Putker, J. S. O'Neill
This study compares the circadian proteome and phosphoproteome of wild-type and CRY-deficient fibroblast cells, finding increased circadian-regulated proteins and stress sensitivity in CRY-deficient cells.
bioRxiv · May 16, 2020Cell Biology