Dissecting Mechanisms of Ligand Binding and Conformational Changes in the Glutamine-Binding Protein
Z. Han, S. Panhans, S. Brameyer, E. Bilgen, M. Ram, A. Herr, A. Narducci, M. Isselstein, P. Harris, O. Brix, P. Con, K. Jung, D. C. Lamb, E. Lerner, D. Griffith, , T. Cordes
This study investigates the ligand binding mechanism of GlnBP in E. coli, finding that conformational changes and ligand binding are correlated, and that the induced-fit mechanism is more consistent with the data than conformational selection.
bioRxiv · Aug 2, 2023Biophysics