RBFOX2 deregulation promotes pancreatic cancer metastasis through alternative splicing
M. Maurin, M. Ranjouri, K. Martin, R. Miner, J. Y. Newberg, D. Du, B. Centeno, J. B. Fleming, X. B. Yu, E. Guccione, M. Black, K. M. Mann
This study identifies RBFOX2 deregulation as a driver of pancreatic cancer metastasis through alternative splicing of ABI1, enhancing cancer cell stemness and invasiveness.
bioRxiv · Jun 1, 2022Cancer Biology