J. Y. Newberg

This study identifies RBFOX2 deregulation as a driver of pancreatic cancer metastasis through alternative splicing of ABI1, enhancing cancer cell stemness and invasiveness.

This paper identifies RBMS3 as a tumor suppressor that cooperates with BRAFV600E to promote malignant lung cancer progression using transposon mutagenesis and CRISPR validation.

The paper identifies metastasis-promoting genes and evolutionary relationships in pancreatic cancer using insertional mutagenesis and single-cell sequencing.

This study uses promoterless transposon mutagenesis to identify tumor suppressor genes driving solid cancers without oncogenic mutations, revealing convergent pathways in cancer progression.

This study uses transposon mutagenesis to identify genetic drivers of keratinocyte transformation and cutaneous squamous cell carcinoma progression in vivo, revealing both known and novel genes involved in the disease.