Author

M. Rigon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

M. Campanella· 3 shared A. Singh· 2 shared D. Faccenda· 2 shared L. Hardy· 2 shared R. Abeti· 2 shared A. Hamacher-Brady· 1 shared B. Kannan· 1 shared D. A. East· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

M. Campanella

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Canine Mammary Tumours (CMTs) exploit Mitochondrial Cholesterol for aggressive reprogramming

L. Hardy, B. Kannan, M. Rigon, G. Benton-Hawthorn, R. L. Previdelli, I. M. Reichler, F. Guscetti, M. P. Kowalewski, M. Campanella

This study shows TSPO's role in aggressive canine mammary tumours by facilitating mitochondrial cholesterol handling, enhancing survival, and reducing Tamoxifen efficacy.

bioRxiv · Jun 23, 2024Cancer Biology

Mitochondria drive microglial NRLP3 inflammasome activation via TSPO

A. Singh, M. Rigon, M. Caldeira, D. Faccenda, D. Xia, J. Lopez-Tremoleda, Z. Falah Hassan Al-Khateeb, T. Guo, R. Abeti, P. Giunti, M. Campanella

This study shows TSPO on mitochondria promotes microglial inflammasome activation by stabilizing NLR proteins, inhibiting mitophagy, and enhancing pro-inflammatory gene expression, leading to excitotoxicity.

bioRxiv · Mar 18, 2024 · PreprintCell Biology

Mitochondria form contact sites with the nucleus to couple pro-survival retrograde response

R. Desai, D. A. East, L. Hardy, M. Rigon, D. Faccenda, M. S. Alvarex, A. Singh, M. Mainenti, L. K. Hussey, R. Bentham, G. Szabadkai, V. Zappulli, G. Dhoot, L. E. Romano, X. Dong, , M. Campanella

The paper shows mitochondria form contact sites with the nucleus to facilitate a pro-survival retrograde response by stabilizing transcription factors like NF-kB.

bioRxiv · May 7, 2020 · PreprintCell Biology