Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
C.-Y. Chung, K. Singh, V. N. Kotiadis…·M. R. Duchen
The paper shows that the m.3243A>G mtDNA mutation activates the PI3K-Akt-mTORC1 pathway, which can be inhibited to reduce mutant mtDNA load and improve cellular function.
R. Desai, D. A. East, L. Hardy…·M. Campanella
The paper shows mitochondria form contact sites with the nucleus to facilitate a pro-survival retrograde response by stabilizing transcription factors like NF-kB.
R. Xu, W. Jones, E. Wilcz-Villega…·K. Bianchi
This study shows that IKKε, a breast cancer oncogene, reprograms mitochondrial function and serine metabolism independently of its canonical signaling role, promoting cancer cell proliferation.