Cell-substrate adhesion drives Scar/WAVE activation and phosphorylation, which controls pseudopod lifetime
S. Singh, P. Thomason, S. Lilla, M. Schacks, Q. Tang, B. Goode, L. Machesky, K. Rottner, R. H. Insall
The paper shows that cell-substrate adhesion drives Scar/WAVE phosphorylation, which limits pseudopod lifetime, independent of chemotactic signals.
bioRxiv · Aug 12, 2019 · PreprintCell Biology