Author

M. Schimpl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Srivastava· 1 shared C. Lindon· 1 shared C. Okoye· 1 shared C. Phillips· 1 shared C. Stubbs· 1 shared D. Barford· 1 shared D. M. Smith· 1 shared D. Spring· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Srivastava

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2 papers

Recent·Most cited

Direct β1/β2 AMPK activation reduces liver steatosis but not fibrosis in a mouse model of non-alcoholic steatohepatitis

K. M. Mather, M. L. Boland, E. L. Rivers, A. Srivastava, M. Schimpl, P. Hemsley, J. Robinson, P. Wan, J. Hansen, J. A. Read, J. L. Trevaskis, D. M. Smith

This study evaluates BI9774, an AMPK activator, in a mouse model of NASH, finding it reduces liver steatosis but not fibrosis and causes cardiac side effects.

bioRxiv · May 30, 2024 · PreprintPharmacology & Toxicology

Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome

R. Eapen, C. Okoye, C. Stubbs, M. Schimpl, T. Tischer, E. J. Fisher, M. Zacharopoulou, F. Ferrer, D. Barford, D. Spring, C. Lindon, C. Phillips, L. S. Itzhaki

This study develops D-box peptides that inhibit APC/C by binding Cdc20, showing they are more potent than Apcin and can drive protein degradation.

bioRxiv · Apr 30, 2024Biochemistry