SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways
E. Eenjes, M. Buscop-van Kempen, A. Boerema-de Munck, L. de Kreij-de Bruin, M. Schnater, D. Tibboel, J. Collins, R. Rottier
This study shows SOX21 inhibits SOX2-driven differentiation of airway progenitor cells in mice and humans, maintaining epithelial cell balance during development and regeneration.
bioRxiv · Jun 4, 2020Cell Biology