Author

R. Rottier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Boerema-de Munck· 1 shared A. Z. Mykytyn· 1 shared B. L. Haagmans· 1 shared D. Schipper· 1 shared D. Tibboel· 1 shared E. Eenjes· 1 shared J. Collins· 1 shared L. de Kreij-de Bruin· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Boerema-de Munck

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The SARS-CoV-2 multibasic cleavage site facilitates early serine protease-mediated entry into organoid-derived human airway cells

A. Z. Mykytyn, T. I. Breugem, S. Riesebosch, D. Schipper, P. B. van den Doel, R. Rottier, M. M. Lamers, B. L. Haagmans

This study shows that the SARS-CoV-2 spike protein's multibasic cleavage site enhances entry into human airway cells via serine proteases, and that blocking these proteases inhibits infection.

bioRxiv · Sep 7, 2020Microbiology

SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways

E. Eenjes, M. Buscop-van Kempen, A. Boerema-de Munck, L. de Kreij-de Bruin, M. Schnater, D. Tibboel, J. Collins, R. Rottier

This study shows SOX21 inhibits SOX2-driven differentiation of airway progenitor cells in mice and humans, maintaining epithelial cell balance during development and regeneration.

bioRxiv · Jun 4, 2020Cell Biology