Epithelial antigen presentation controls commensal-specific intraepithelial T-cells in the gut
T. Brabec, M. Schwarzer, K. Kovacova, M. Dobesova, D. Schierova, J. Brezina, I. Pacakova, D. Srutkova, O. Ben-Nun, Y. Goldfarb, I. Splichalova, M. Kolar, J. Abramson, D. Filipp, J. Dobes
This study shows that MHCII on intestinal epithelial cells drives commensal-specific intraepithelial T-cells and regulates epithelial turnover.
bioRxiv · Aug 21, 2022Immunology