Author

J. Abramson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Noronha· 1 shared A. Paz· 1 shared A. Tennenhouse· 1 shared D. Fass· 1 shared D. Filipp· 1 shared D. Joseph· 1 shared D. Schierova· 1 shared D. Srutkova· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBioengineering

A. Noronha

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Biochemical characterization of a GDP-mannose transporter from Chaetomium thermophilum

G. T. R. Premageetha, K. Dhanabalan, S. Bose, L. Manjunath, D. Joseph, A. Paz, S. Grandfield, V. Nayak, L. M. Bredeston, J. Abramson, R. Subramanian

The paper characterizes CtVrg4, a GDP-mannose transporter from Chaetomium thermophilum, showing enhanced thermal stability and phosphatidylinositol lipid binding.

bioRxiv · Jan 13, 2023 · PreprintBiochemistry

Epithelial antigen presentation controls commensal-specific intraepithelial T-cells in the gut

T. Brabec, M. Schwarzer, K. Kovacova, M. Dobesova, D. Schierova, J. Brezina, I. Pacakova, D. Srutkova, O. Ben-Nun, Y. Goldfarb, I. Splichalova, M. Kolar, J. Abramson, D. Filipp, J. Dobes

This study shows that MHCII on intestinal epithelial cells drives commensal-specific intraepithelial T-cells and regulates epithelial turnover.

bioRxiv · Aug 21, 2022Immunology

Reliable energy-based antibody humanization and stabilization

A. Tennenhouse, L. Khmelnitsky, R. Khalaila, N. Yeshaya, A. Noronha, M. Lindzen, E. Makowski, I. Zaretsky, Y. Fridmann Sirkis, Y. Galon-Wolfenson, P. M. Tessier, J. Abramson, Y. Yarden, D. Fass, S. J. Fleishman

The paper introduces CUMAb, a computational method for humanizing antibodies that improves stability and binding by systematically grafting CDRs onto human frameworks and ranking designs using Rosetta simulations.

bioRxiv · Aug 14, 2022Bioengineering

MicroED structure of lipid-embedded mammalian mitochondrial voltage dependent anion channel

M. W. Martynowycz, F. Khan, J. Hattne, J. Abramson, T. Gonen

The paper determines the near-atomic structure of mouse VDAC using MicroED after milling microcrystals grown in a lipid matrix.

bioRxiv · Sep 17, 2020Biophysics