Author

M. T. Huxley

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. D. Abell· 1 shared A. P. Thompson· 1 shared B. I. Gaiser· 1 shared C. J. Sumby· 1 shared J. B. Bruning· 1 shared K. J. Lee· 1 shared K. L. Wegener· 1 shared S. W. Polyak· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. D. Abell

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintMar 26, 2023

Fortuitous in vitro compound degradation produces a tractable hit against Mycobacterium tuberculosis dethiobiotin synthetase: a cautionary tale of what goes in, does not always come out

W. Salaemae, A. P. Thompson, B. I. Gaiser…·K. L. Wegener

The paper describes how a fragment compound was inadvertently modified in crystal conditions, leading to a potent inhibitor of Mycobacterium tuberculosis dethiobiotin synthetase.

DOI 10.1101/2023.03.26.531482

experimental assaydrug response / drug discovery

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