BiophysicsbioRxiv
Water inside the selectivity filter of a K+ ion channel: structural heterogeneity, picosecond dynamics, and hydrogen-bonding
M. J. Ryan, L. Gao, F. I. Valiyaveetil…·M. T. Zanni
This study uses 2D IR spectroscopy and simulations to analyze water dynamics and K+ ion behavior in the KcsA channel selectivity filter, revealing structural heterogeneity and distinct reorientation timescales.
DOI 10.1021/jacs.3c11513