BiochemistrybioRxiv
Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome
K. Zhang, I. N. Zheludev, R. J. Hagey…·R. Das
The paper uses cryo-EM and ASO experiments to study the SARS-CoV-2 FSE structure and its potential as an antiviral target, finding a complex tertiary structure but challenges in effective inactivation.
DOI 10.1038/s41594-021-00653-y