Loss of STIM1 and STIM2 in salivary glands disrupts ANO1 function but does not induce Sjogren's disease
G.-Y. Son, A. Zou, A. Wahl, K. T. Huang, M. Vinu, S. Zorgit, F. Zhou, L. Wagner, Y. Idaghdour, D. I. Yule, S. Feske, R. S. Lacruz
This study shows that loss of STIM1 and STIM2 in salivary glands reduces ANO1 function and saliva production but does not cause Sjogren's disease, suggesting a link between SOCE and TLR8 signaling.
bioRxiv · Jan 8, 2024Physiology