The Dual Roles of the CXCL10-CXCR3 Axis and Its Therapeutic Potential in Osteosarcoma
B. B. Gyau, J. Wang, X. Chen, M. A. Clement, Z. D. Man, A. M. Major, J. Xu, M. Weiser, J. M. Hicks, T.-K. Man
This study investigates the dual role of the CXCL10-CXCR3 axis in osteosarcoma, showing it promotes tumor growth but also recruits immune cells, suggesting CXCR3 inhibition could target metastasis.
bioRxiv · Jun 4, 2024 · PreprintCancer Biology