Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal coronaviruses
A. Rebendenne, P. Roy, B. Bonaventure, A. L. Chaves Valadao, L. Desmarets, Y. Rouille, M. Tauziet, M. Arnaud-Arnould, D. Giovannini, Y. Lee, P. DeWeirdt, M. Hegde, F. Garcia de Gracia, J. McKellar, M. Wencker, , C. Goujon
The paper performs bidirectional CRISPR screens to identify host factors regulating SARS-CoV-2, MERS-CoV, and seasonal coronaviruses, revealing new anti-viral proteins and general coronavirus cofactors.
bioRxiv · May 19, 2021Microbiology