Pulmonary Fibrosis Ferret Model Demonstrates Sustained Fibrosis, Restrictive Physiology, and Aberrant Repair
J. E. Peabody Lever, Q. Li, N. Pavelkova, S. S. Hussain, S. Bakshi, J. Q. Ren, L. I. Jones, J. P. Kennemur, M. Weupe, J. Campos-Gomez, L. Tang, J. M. Peabody Lever, D. Wang, D. D. Stanford, J. Foote, , S. M. Rowe
This study shows that bleomycin-exposed ferrets develop sustained pulmonary fibrosis, restrictive lung physiology, and airway remodeling similar to human IPF.
bioRxiv · Jun 4, 2024 · PreprintPhysiology