Author

M. Zafferani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. E. Hargrove· 2 shared A. A. Kennedy· 1 shared A. G. Monaghan· 1 shared A. W. Tai· 1 shared B. S. Tolbert· 1 shared C. Haddad· 1 shared C. Shema Mugisha· 1 shared D. Muralidharan· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

A. E. Hargrove

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2 papers

Recent·Most cited

RT-qPCR as a screening platform for mutational and small molecule impacts on structural stability of RNA tertiary structures

M. Zafferani, D. Muralidharan, A. E. Hargrove

The paper develops a high-throughput RT-qPCR platform to assess how mutations and small molecules affect RNA triple helix stability, using MALAT1 as a model.

bioRxiv · Jan 16, 2022Biophysics

Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures

M. Zafferani, C. Haddad, L. Luo, J. Davila-Calderon, L. Yuan-Chiu, C. Shema Mugisha, A. G. Monaghan, A. A. Kennedy, J. D. Yesselman, R. R. Gifford, A. W. Tai, S. B. Kutluay, M.-L. Li, G. Brewer, B. S. Tolbert, A. E. Hargrove

This study identifies amilorides as small molecules that inhibit SARS-CoV-2 replication by targeting conserved RNA structures in the 5-UTR region.

bioRxiv · Dec 5, 2020Microbiology