Cancer BiologybioRxivPreprint
A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress
O. Y. Teran Pumar, M. R. Zanotelli, M.-c. J. Lin…·K. F. Wilson
This study identifies a multiprotein complex, DockTOR, that sustains AKT and mTOR/S6K activity in cancer cells under stress, enabling survival through a mechanism independent of growth factor signaling.
DOI 10.1101/2023.01.03.522657