Cell BiologybioRxivPreprint
Running Kinesin-1 shapes the microtubule acetylation gradient
M. Andreu-Carbo, C. Egoldt, M.-C. Velluz, C. Aumeier
The paper shows that kinesin-1-induced damage sites regulate microtubule acetylation by enabling HDAC6 entry, while TAT1 acetylation is independent of kinesin-1, leading to an exponential acetylation gradient in cells.
DOI 10.1101/2022.12.01.518806