MicrobiologybioRxivPreprint
E3 ubiquitin ligase SKP2 limits autophagy during S. aureus infection
Abhishek Kumar Singh, Madina Baglanova, Eylin Topfstedt…·Ulrike Seifert
This study shows that SKP2 limits autophagy during S. aureus infection by stabilizing and translocating to the cytoplasm, reducing LC3-II levels and intracellular bacterial survival.
DOI 10.1101/2025.11.03.686196