NeurosciencebioRxivPreprint
Hyperexcitability precedes CA3 hippocampal neurodegeneration in a dox-regulatable TDP-43 mouse model of ALS-FTD.
William Rodemer, Irene Ra, Elizabeth Jia…·Virginia M.‐Y. Lee
This study shows that hyperexcitability precedes neurodegeneration in a TDP-43 mouse model of ALS-FTD, but targeting hyperexcitability does not prevent neuron loss.
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