Pharmacology & ToxicologybioRxivPreprint
Sparse Phosphorylatable Residues, Tuned by Agonist Chemotype, Shapes GPCR Signaling
M. K. Borah, Sarfraz Ahmed, Mahek Agrawal…·Mithu Baidya
This study shows that GPCR signaling diversity can arise from a sparse set of phosphorylation sites rather than an extensive barcode, with ligand chemotype influencing their functional impact.
DOI 10.64898/2026.10.06.756976