Author

Malcolm Perry

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Genomics· 1

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:multiple species· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

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Boris Lenhard· 1 shared Elizabeth Ing-Simmons· 1 shared Ge Tan· 1 shared Matthias Merkenschlager· 1 shared Nathan Harmston· 1 shared

Activity by Year

2016-2016 · peak 1/yr

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1 shared paperGenomics

Boris Lenhard

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintAug 28, 2016

Topologically associated domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation

Nathan Harmston, Elizabeth Ing-Simmons, Ge Tan…·Boris Lenhard

The paper shows that genomic regulatory blocks (GRBs) align with topologically associating domains (TADs) in metazoan genomes, suggesting ancient, conserved structures involved in developmental regulation.

DOI 10.1101/042952

multiple speciesDNA methylation

𝕏 PostBluesky