Cancer BiologybioRxivPreprint
Fenretinide targets GATA1 to induce cytotoxicity in GATA1 positive Acute Erythroid and Acute Megakaryoblastic Leukemic cells.
Yasharah Raza, Manal Elmasry, Guoying Yu…·Chiara Luberto
This paper identifies Fenretinide as a GATA1-targeting agent that induces cytotoxicity in M6 and M7 AML cells by causing GATA1 loss and overcomes chemotherapeutic resistance.
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