Molecular BiologybioRxivPreprint
Elucidating the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors
Jody Pacalon, Guillaume Audic, Justine Magnat…·Jérémie Topin
The paper identifies amino acids involved in ligand entry and binding to Drosophila Orco using molecular modeling and electrophysiology, revealing a mechanism for ligand translocation and high selectivity.