Marat Mufteev

The paper identifies miRNAs selectively loaded into extracellular vesicles from healthy human astrocytes and links them to neurodevelopmental disorders.

The paper investigates how mRNA half-life buffers transcription rate changes in Rett syndrome models, identifying post-transcriptional mechanisms in human and mouse neurons.

The paper measures transcription rate and mRNA half-life changes during human neuronal development and identifies transcriptional buffering as the most prevalent mode of gene regulation.

This study examines the effects of MECP2 mutations on neuronal and network phenotypes in human stem cell-derived excitatory neurons, showing a spectrum of morphological, electrophysiological, and circuitry changes based on mutation severity.

The paper identifies TIA1 mRNA targets during human neuronal development and shows that TIA1 binding is associated with translation repression and neurodevelopmental gene regulation.