Marc Robinson-Rechavi

This study shows that estrogen pollution affects gene expression and delays sex differentiation in grayling, with stronger effects in females and some feminization of males.

The paper shows orthologs conserve tissue-specificity across species, while paralogs diverge rapidly, supporting a model where duplication leads to new functions through expression divergence.

This paper introduces state aggregation to speed up likelihood computations in codon models without introducing bias, showing up to 6.8x speedup and high correlation with full likelihood results.

This study benchmarks nine gene expression tissue-specificity metrics to evaluate their ability to distinguish gene categories, robustness to tissue selection, and capture of evolutionary conservation signal.

The paper introduces a new statistical method, 2DNS, to detect selection acting on human biological pathways by analyzing genetic diversity and evolutionary constraints.

The paper reviews challenges in comparative transcriptomics for Evo-Devo and discusses efforts to address them through bioinformatics tools and the Bgee database.

The paper examines how protein-coding gene evolution varies across tissues in humans and mice, finding that purifying selection and tissue-specific expression patterns influence evolutionary rates.

The paper evaluates two methods for detecting diversification patterns under scenarios with rate shifts and mass extinctions, finding lineage shifts are better detected than mass extinctions.