MicrobiologybioRxivPreprint
An imputed ancestral reference genome for the Mycobacterium tuberculosis complex better captures structural genomic diversity for reference-based alignment workflows
Luke B Harrison, Vivek Kapur, Marcel A Behr
The paper introduces an imputed ancestral reference genome (MTBC0) for the Mycobacterium tuberculosis complex that improves read mapping and SNP calling compared to existing references.
DOI 10.1101/2023.09.07.556366