Author

Margaret Dugoni

Villanova University

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Synthetic Biology· 1

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1

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Eric WargaiD· 1 shared Isioma Enwerem-LacklandiD· 1 shared Jacob J. ElmeriD· 1 shared Karmella Ann HaynesiD· 1 shared

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Synthetic BiologybioRxivPreprintNov 1, 2021

Targeted regulation of plasmid DNA expression in eukaryotic cells with a methylated-DNA-binding activator

Isioma Enwerem-Lackland, Eric Warga, Margaret Dugoni…·Karmella Ann Haynes

The paper introduces a system to regulate plasmid DNA expression in eukaryotic cells by targeting methylated DNA using a fusion protein that binds to GATC motifs.

DOI 10.1101/2021.11.01.466616

DNA methylationexperimental assay

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