Molecular BiologybioRxiv
Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression
Sarah K. Sasse, Margaret Gruca, Mary Ann Allen…·Anthony N. Gerber
The paper uses GRO-seq to show glucocorticoids rapidly repress transcription without local GR occupancy and induce anti-inflammatory effects through GR-NF-kB cooperation.
44 citations