Developmental BiologyNature MetabolismPeer-reviewed
Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development
Ana Lima, Gabriele Lubatti, Jörg Patrick Burgstaller…·Tristan A. Rodríguez
The paper identifies mitochondrial defects in eliminated cells during early mouse development and shows that cell competition removes cells with mitochondrial DNA mutations and sequence changes.