BiochemistryPharmaceuticalsPeer-reviewed
Discovery and characterization of novel inhibitors against ALS-related SOD1(A4V) aggregation through screening of a chemical library using Differerential Scanning Fluorimetry (DSF)
Maria Giannakou, Ifigeneia Akrani, Angeliki Tsoka…·Dimitris G. Hatzinikolaou
This paper identifies compounds that affect SOD1(A4V) thermal stability using DSF, with some showing potential to stabilize or destabilize the protein.