NeuroscienceScientific ReportsPeer-reviewed
Deleting a UBE3A substrate rescues impaired hippocampal physiology and learning in Angelman syndrome mice
Gabrielle L. Sell, Wendy Xin, Emily K. Cook…·Seth S. Margolis
This study identifies Ephexin5 as a key UBE3A substrate whose removal rescues hippocampal dysfunction and behavioral deficits in Angelman syndrome mouse models.
25 citations