BiophysicsPLoS BiologyPeer-reviewed
Structural elucidation of the haptoglobin-hemoglobin clearance mechanism by macrophage scavenger receptor CD163
Ching-Shin Huang, Hui Wang, Joshua B. R. White…·Lidia Mosyak
This study determines the cryo-EM structures of CD163 in complex with haptoglobin-hemoglobin, revealing its trimeric structure and calcium-dependent mechanism for HpHb clearance.