Molecular BiologybioRxivPreprint
SUMOylation controls the rapid transcriptional reprogramming induced by anthracyclines in Acute Myeloid Leukemias
Mathias Boulanger, Chamseddine Kifagi, Marko Ristic…·Guillaume Bossis
This study shows that Daunorubicin induces transcriptional changes in AML cells through SUMO-dependent chromatin reconfiguration, affecting genes related to proliferation, death, and immunity.
DOI 10.1101/2022.04.19.488613