Human chronic inflammation is orchestrated by spatially restricted inflammation-activated Dendritic cells
Jake R. Thomas, Jessica Haub, Alina Hunecke, Jiangyan Yu, P. Maier, M. Zhang, B.E.F. Pregler, Markus Raspe, S. Strieth, M. Schneider, V. Schäfer, C. Pizzaro, D. Skowasch, Florent Ginhoux, M. Toma, , A. Schlitzer
This study identifies a novel inflammation-associated dendritic cell state in human chronic inflammation and shows its spatial restriction and therapeutic relevance.
bioRxiv · May 19, 2025 · PreprintImmunology