Author
Fraunhofer Institute for Translational Medicine and Pharmacology
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Johanna Huchting, Arjen Weller, Moyra Schweizer…·Aimo Kannt
The paper optimizes and evaluates two cell-based assays for degrader discovery, finding that the signal rescue assay reliably identifies active degraders and filters out non-specific compounds.
Maria Kuzikov, Stefano Morasso, Jeanette Reinshagen…·Andrea Zaliani
The paper identifies CPI-169 as a competitive inhibitor of SARS-CoV-2 PLpro that targets the same binding site as GRL-0617, through a drug repurposing screening approach that accounts for redox-sensitivity.
Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen…·Andrea Zaliani
The paper identifies 62 new inhibitors of SARS-CoV-2 3CL-Pro through a compound repurposing screen and validates their activity using X-ray crystallography.