GeneticsPLoS ONEPeer-reviewed
NaV1.1 and NaV1.6 selective compounds reduce the behavior phenotype in a novel zebrafish model for Dravet Syndrome
Wout J. Weuring, Sakshi Singh, Linda Volkers…·Bobby P.C. Koeleman
This study develops a zebrafish model for Dravet Syndrome and tests compounds that selectively target Nav1.1 or Nav1.6 channels, showing both reduce seizure-like behavior.
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