Complement C3aR deletion does not attenuate neurodegeneration in a tauopathy model or alter acute inflammation-induced gene expression changes in the brain
Yuanyuan Wang, Shristi Pandey, Martin Weber, Man Kin Choy, Tiffany Z. Wu, Tania Chernov-Rogan, Hai Ngu, Oded Foreman, Luke Xie, Jesse E. Hanson
This study shows that deleting C3aR does not reduce neurodegeneration in a tauopathy model or alter gene expression changes during acute inflammation.
bioRxiv · Jun 16, 2025 · PreprintNeuroscience