Yuanyuan Wang

This study identifies Fibulin-2 as a matrix cue that transduces fibrotic ECM remodeling into mitochondrial metabolic reprogramming in kidney fibrosis.

This study identifies Mfap2 as a key ECM component that regulates kidney repair by linking mechanical cues to metabolic reprogramming through Esr2-mediated transcriptional control.

This study shows that deleting C3aR does not reduce neurodegeneration in a tauopathy model or alter gene expression changes during acute inflammation.

The paper constructs an integrated atlas of astrocytes from human and mouse neurodegenerative disease models, identifying conserved and divergent subtypes across species.