BiochemistrybioRxivPreprint
Identification of key Y4R residues enables the discovery of selective non-peptide small-molecule agonists
Tim Pelczyk, Corinna Schüß, Mateusz Sklodowski…·Annette Gabriele Beck‐Sickinger
This study identifies key Y4R residues and discovers selective non-peptide small-molecule agonists through molecular docking, residue replacement, and ultra-large library screening.
DOI 10.64898/2026.04.27.721169