GenomicsNucleic Acids ResearchPeer-reviewed
A mutational gradient drives somatic mutation accumulation in mitochondrial DNA and influences germline polymorphisms and genome composition
Mónica Sánchez-Contreras, Mariya T. Sweetwyne, Brendan F. Kohrn…·Scott R. Kennedy
The paper identifies a mutational gradient in mtDNA that correlates with replication and influences mutation accumulation and genome composition.