Cell BiologybioRxivPreprint
The Anaphase Promoting Complex targets the toxic protein Progerin for ubiquitin-dependent degradation via autophagy
Valeria Martinez, Matthew Lubachowski, Zoe E. Gillespie…·Christopher H. Eskiw
This study identifies the Anaphase Promoting Complex (APC) as a mediator of progerin degradation via autophagy in Hutchinson-Gilford Progeria Syndrome.
DOI 10.64898/2026.07.23.740245