MitoPerturb-Seq identifies common and gene-specific single-cell responses to mitochondrial DNA depletion and heteroplasmy
Stephen P. Burr, Kathryn Auckland, Angelos Glynos…·Jelle van den Ameele
Author
University of Cambridge
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Stephen P. Burr, Kathryn Auckland, Angelos Glynos…·Jelle van den Ameele
Christopher J. Carnie, Maximilian J. Götz, Chloe S. Palma-Chaundler…·Stephen P. Jackson
This study identifies DCTD and TOPORS as key factors in decitabine cytotoxicity by showing their roles in DPC formation and repair.
Anne Ramsay Bowden, David A. Morales-Juarez, Matylda Sczaniecka-Clift…·Stephen P. Jackson
The paper assesses how p53 status affects CRISPR-Cas9 screen performance by comparing wild-type and TP53 knockout cells, showing that optimal design can still yield reliable results.