NeurosciencebioRxivPreprint
FMRP regulates adult human cortical neuron excitability via cyclic-AMP signalling
Max J J Knops, Soraya Meftah, Max A Wilson…·Sam A. Booker
This study shows that FMRP depletion in human neurons causes cyclic-AMP-dependent hyperexcitability, which can be corrected by inhibiting phosphodiesterase 4D.
DOI 10.1101/2025.10.14.682273