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Maxime Basse

Harvard University

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Molecular Biology· 1

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Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Organism:virus· 1

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Dianzhuo WangiD· 1 shared Eugene I. ShakhnovichiD· 1 shared

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1 paper

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Molecular BiologybioRxivPreprintApr 10, 2025

Spatial Clustering of Interface Residues Enhances Few-Shot Prediction of Viral Protein Binding

Maxime Basse, Dianzhuo Wang, Eugene I. Shakhnovich

The paper introduces PROXICLUST, a method that uses spatial clustering of interface residues to predict viral protein binding affinities across larger mutation spaces using smaller datasets.

1 citation

virusprotein structure

𝕏 PostBluesky